APOC1P1-3

Gene basic information

symbol APOC1P1
name apolipoprotein C1 pseudogene 1
location 19q13.32
alias_symbol
alias_name
Tissuebreast,
Cancerbreast cancer,


Description

LincRNA APOC1P1-3 is over-expressed in breast cancer tissues and cell lines. Hypomethylation in the C/G site may contribute to its upregulation. APOC1P1-3 expression is positively associated with tumor size. Upregulation of APOC1P1-3 inhibits cell apoptosis, but not affects cell cycles. Furthermore, the variation of APOC1P1-3 could affect caspase-3 activation. Besides, APOC1P1-3 can bind α-tubulin and modify its acetylation, thus inhibit cell apoptosis (1).


Cancer related information

download as excel csv txt

LncRNA tissue cancer type expression level oncogene/suppress gene pathway binding gene/factor associated gene/factor proliferation apoptosis migration EMT invasion metastasis prognosis tag PMID
0 APOC1P1-3 breast breast cancer up onco α-tubulin caspase-3- - epigenetic modification 27228351

Expression profile

adipose adrenal brain breast colon heart kidney leukocyte liver lung lymph node ovary prostate skeletal muscle testis thyroid tissue 0 1 2 3 4 5 6 fpkm 0.1 0.4 0.4 0.3 0.0 0.0 0.1 0.1 6.0 0.1 0.3 0.0 0.3 0.3 0.2 0.0 APOC1P1-3

Expression profile in human body map

Genomic feature visualization


Sequence

External link



Literature

[1]. Liao XH, Wang JG, Li LY, Zhou DM, Ren KH, et al. (2016). Long intergenic non-coding RNA APOC1P1-3 inhibits apoptosis by decreasing α-tubulin acetylation in breast cancer. Cell Death Dis 7: e2236. link pubmed



© Bioinformatics Group of XTBG