BACE1-AS

Gene basic information

symbol BACE1-AS
name BACE1 antisense RNA
location 11q23.3
alias_symbol FJ573250|NCRNA00177|BACE1-AS1
alias_name non-protein coding RNA 177
Tissueovary,
Cancerovarian cancer,


Description

LncRNA BACE1-AS in the anisomycin-treated ovarian cancer stem cells (OCSCs) is significantly elevated compared to the dimethylsulfoxide (DMSO) treated OCSCs or untreated OCSCs after 72 h. Anisomycin can stimulate expression of BACE1-AS and apoptosis-related proteins in OCSCs. Moreover, anisomycin can inhibit OCSCs xenograft growth. Accordingly, silencing of lncRNA BACE1-AS expression can weaken the effects of anisomycin in OCSCs (1).


Cancer related information

download as excel csv txt

LncRNA tissue cancer type expression level oncogene/suppress gene pathway binding gene/factor associated gene/factor proliferation apoptosis migration EMT invasion metastasis prognosis tag PMID
0 BACE1-AS ovary ovarian cancer / TS - - chemotherapy resistance,cancer stem cells 26783004

Expression profile

adipose adrenal brain breast colon heart kidney leukocyte liver lung lymph node ovary prostate skeletal muscle testis thyroid tissue 0 2 4 6 8 fpkm 1.0 3.0 4.0 4.0 2.0 2.0 3.0 2.0 1.0 1.0 4.0 8.0 5.0 9.0 7.0 3.0 BACE1-AS

Expression profile in human body map

Genomic feature visualization


Sequence

External link



Literature

[1]. Chen Q, Liu X, Xu L, Wang Y, Wang S, et al. (2016). Long non-coding RNA BACE1-AS is a novel target for anisomycin-mediated suppression of ovarian cancer stem cell proliferation and invasion. Oncol Rep 35(4): 1916-24. link pubmed



© Bioinformatics Group of XTBG