BC032469

Gene basic information

SymbolBC032469
Tissuestomach,
Cancergastric cancer,


Description

LncRNA BC032469 is up-regulated in gastric cancer tissues, and is clinically associated with tumor size, differentiation and survival of gastric cancer patients. Downregulation of BC032469 results in a significant inhibition of proliferation in vitro and in vivo. Mechanistically, BC032469 could up-regulate hTERT by directly binding to miR-1207-5p and effectively functioning as a sponge for miR-1207-5p (1)


Cancer related information

download as excel csv txt

LncRNA tissue cancer type expression level oncogene/suppress gene pathway binding gene/factor associated gene/factor proliferation apoptosis migration EMT invasion metastasis prognosis tag PMID
0 BC032469 stomach gastric cancer up onco miR-1207-5p hTERT+ + - 26549025

Expression profile

adipose adrenal brain breast colon heart kidney leukocyte liver lung lymph node ovary prostate skeletal muscle testis thyroid tissue 0.0 0.2 0.4 0.6 0.8 1.0 fpkm 0.0 0.3 0.1 0.0 0.1 0.1 0.2 0.0 1.0 0.1 0.0 0.2 0.0 0.0 0.1 0.1 BC032469

Expression profile in human body map

TCGA-BLCA TCGA-BRCA TCGA-CESC TCGA-HNSC TCGA-KICH TCGA-KIRC TCGA-KIRP TCGA-LIHC TCGA-LUAD TCGA-LUSC TCGA-PRAD TCGA-STAD TCGA-THCA TCGA-UCEC tissue 0.0 0.2 0.4 0.6 0.8 1.0 fpkm BC032469 type normal tumor

Expression profile in TCGA


Genomic feature visualization


Sequence

Literature

[1]. Lü MH, Tang B, Zeng S, Hu CJ, Xie R, et al. (2016). Long noncoding RNA BC032469, a novel competing endogenous RNA, upregulates hTERT expression by sponging miR-1207-5p and promotes proliferation in gastric cancer. Oncogene 35(27): 3524-34. link pubmed



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