BX647187

Gene basic information

SymbolBX647187
Tissueprostate,
Cancerprostate cancer,


Description

LncRNA BX647187 is up-regulated in prostate cancer cells, which is positively regulated by Hec1. Further studies find that BX647187 is positive with the expression of caspase-3, caspase-9 and Bax, while negative with Bcl-2. But the expression of caspase-8 has no obvious change. These results indicate that BX647187 affects apoptosis via intrinsic apoptotic pathway (1).


Cancer related information

download as excel csv txt

LncRNA tissue cancer type expression level oncogene/suppress gene pathway binding gene/factor associated gene/factor proliferation apoptosis migration EMT invasion metastasis prognosis tag PMID
0 BX647187 prostate prostate cancer up onco +Hec1,caspase-3+,caspase-9+,Bax+,Bcl-2- - 26612002

Literature

[1]. Wang H, Gao X, Lu X, Wang Y, Ma C, et al. (2015). The mitotic regulator Hec1 is a critical modulator of prostate cancer through the long non-coding RNA BX647187 in vitro. Biosci Rep 35(6). link pubmed



© Bioinformatics Group of XTBG