CAHM

Gene basic information

symbol CAHM
name colon adenocarcinoma hypermethylated (non-protein coding)
location 6q26
alias_symbol LINC00468
alias_name long intergenic non-protein coding RNA 468
Tissuecolorectum,
Cancercolorectal cancer,


Description

LncRNA CAHM is hypermethylation in neoplastic colorectal tissue, and blood from CRC patients. CAHM methylation correlates with of loss expression of CAHM RNA in colorectal tissue and CRC cell lines. Moreover, CAHM methylation levels in blood reflect disease severity (1).


Cancer related information

download as excel csv txt

LncRNA tissue cancer type expression level oncogene/suppress gene pathway binding gene/factor associated gene/factor proliferation apoptosis migration EMT invasion metastasis prognosis tag PMID
0 CAHM colorectum colorectal cancer down / epigenetic modification 24799664

Expression profile

adipose adrenal brain breast colon heart kidney leukocyte liver lung lymph node ovary prostate skeletal muscle testis thyroid tissue 0 1 2 3 4 5 fpkm 0.5 0.7 5.0 0.4 0.5 0.4 0.6 0.4 0.1 0.9 0.6 0.4 2.0 0.9 2.0 1.0 CAHM

Expression profile in human body map

TCGA-BLCA TCGA-BRCA TCGA-CESC TCGA-HNSC TCGA-KICH TCGA-KIRC TCGA-KIRP TCGA-LIHC TCGA-LUAD TCGA-LUSC TCGA-PRAD TCGA-STAD TCGA-THCA TCGA-UCEC tissue 0.0 0.1 0.2 0.3 0.4 0.5 0.6 fpkm CAHM type normal tumor

Expression profile in TCGA


Genomic feature visualization


Sequence

External link



Literature

[1]. Pedersen SK, Mitchell SM, Graham LD, McEvoy A, Thomas ML, et al. (2014). CAHM, a long non-coding RNA gene hypermethylated in colorectal neoplasia. Epigenetics 9(8): 1071-82. link pubmed



© Bioinformatics Group of XTBG