CCHE1

Gene basic information

symbol CCEPR
name cervical carcinoma expressed PCNA regulatory lncRNA
location 10q21.1
alias_symbol CCHE1
alias_name cervical carcinoma high-expressed lncRNA 1
Tissuecervix,
Cancercervical cancer,


Description

LncRNA CCHE1 is up-regulated in cervical cancer tissues and predicts poor prognosis of cervical cancer patients. Correlation regression analysis shows that increased CCHE1 expression is significantly correlated with larger tumor size, advanced FIGO stage, higher SCC-Ag and uterine corpus invasion. CCHE1 promotes the proliferation of cervical cancer cells and the effect is dependent upon CCHE1 physically associating with PCNA mRNA thus to up-regulate the expression of PCNA (1).


Cancer related information

download as excel csv txt

LncRNA tissue cancer type expression level oncogene/suppress gene pathway binding gene/factor associated gene/factor proliferation apoptosis migration EMT invasion metastasis prognosis tag PMID
0 CCHE1 cervix cervical cancer up onco PCNA+ + - 25921283

External link



Literature

[1]. Yang M, Zhai X, Xia B, Wang Y, Lou G (2015). Long noncoding RNA CCHE1 promotes cervical cancer cell proliferation via upregulating PCNA. Tumour Biol 36(10): 7615-22. link pubmed



© Bioinformatics Group of XTBG