Gene basic information

Cancerprostate cancer,


LncRNA CTB-89H12.4 is up-regulated in prostate cancer cell lines. Depletion of PTEN transcript by siRNAs reduces the expression of CTB-89H12.4. The depletion of CTB-89H12.4 transcripts also reduces the expression of two other protein-coding genes (PCGs), VAPA and SERINC1, sponge-mRNAs of PTEN (1).

Cancer related information

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LncRNA tissue cancer type expression level oncogene/suppress gene pathway binding gene/factor associated gene/factor proliferation apoptosis migration EMT invasion metastasis prognosis tag PMID
0 CTB-89H12.4 prostate prostate cancer up / PTEN 26975529

Expression profile

adipose adrenal brain breast colon heart kidney leukocyte liver lung lymph node ovary prostate skeletal muscle testis thyroid tissue 0 1 2 3 4 5 6 fpkm 2.0 4.0 2.0 2.0 2.0 1.0 3.0 0.7 1.0 6.0 6.0 2.0 4.0 1.0 2.0 2.0 CTB-89H12.4

Expression profile in human body map

Genomic feature visualization



[1]. Du Z, Sun T, Hacisuleyman E, Fei T, Wang X, et al. (2016). Integrative analyses reveal a long noncoding RNA-mediated sponge regulatory network in prostate cancer. Nat Commun 7: 10982. link pubmed

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