CTD903

Gene basic information

SymbolCTD903
Tissuecolorectum,
Cancercolorectal cancer,


Description

LncRNA CTD903 expression is up-regulated in colorectal cancer tissues. The higher CTD903 group shows more percentages of colon cancers comparing with rectum cancers, less mucinous tumors, and smaller tumor size. CTD903 high expression group has a significantly longer recurrence-free survival (RFS). Overexpression of CTD903 impairs cell invasion, migration and proliferation. CTD903 represses Wnt/β-catenin signaling and inhibits EMT-associated transcription factors twist and snail expression (1).


Cancer related information

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LncRNA tissue cancer type expression level oncogene/suppress gene pathway binding gene/factor associated gene/factor proliferation apoptosis migration EMT invasion metastasis prognosis tag PMID
0 CTD903 colorectum colorectal cancer up TS Wnt/β-catenin- Twist-, Snail-,β-catenin-,ZO-1+ - - - - 27035092

Literature

[1]. Yuan Z, Yu X, Ni B, Chen D, Yang Z, et al. (2016). Overexpression of long non-coding RNA-CTD903 inhibits colorectal cancer invasion and migration by repressing Wnt/β-catenin signaling and predicts favorable prognosis. Int J Oncol 48(6): 2675-85. link pubmed



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