| Symbol | DQ786227 |
| Tissue | lung, |
| Cancer | lung cancer, |
The role of lncRNA DQ786227 in transformed human bronchial epithelial cells induced by benzo(a)pyrene is investigated. The transformed cell model is established using the BEAS-2B cell line, the study finds that DQ786227 is high and changed during the transformation of BEAS-2B cells. Silencing of DQ786227 expression in malignant transformed BEAS-2B cells leads to inhibition of cell proliferation and colony formation, and increased apoptosis. Moreover, DQ786227 dramatically promotes the ability of BEAS-2B-T cells to form colonies in vitro and develop tumors in nude mice (1).
| LncRNA | tissue | cancer type | expression level | oncogene/suppress gene | pathway | binding gene/factor | associated gene/factor | proliferation | apoptosis | migration | EMT | invasion | metastasis | prognosis | tag | PMID | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0 | DQ786227 | lung | lung cancer | up | onco | + | - | chemical substances | 24084393 |