Gene basic information

symbol TMPOP2
name thymopoietin pseudogene 2
location 16q23.1
alias_symbol lncRNA-EBIC
alias_name EZH2-binding lncRNA in cervical cancer
Cancercervical cancer,


LncRNA EBIC is up-regulated in cervical cancer (CC). EBIC silencing impairs CC cells migration and invasion. Moreover, EBIC can bind to EZH2. Furthermore, EBIC could inhibit E-cadherin by associating with EZH2, therefore EBIC might act as a facilitator in recruiting EZH2 to the promoter region of E-cadherin. EBIC and EZH2 may be two interdependent components of the H3K27me3 process (1)

Cancer related information

download as excel csv txt

LncRNA tissue cancer type expression level oncogene/suppress gene pathway binding gene/factor associated gene/factor proliferation apoptosis migration EMT invasion metastasis prognosis tag PMID
0 EBIC cervix cervical cancer up onco EZH2 E-cadherin- + + 25007342

Expression profile

adipose adrenal brain breast colon heart kidney leukocyte liver lung lymph node ovary prostate skeletal muscle testis thyroid tissue 0 1 2 3 4 5 fpkm 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 5.0 0.0 EBIC

Expression profile in human body map

Genomic feature visualization


External link


[1]. Sun NX, Ye C, Zhao Q, Zhang Q, Xu C, et al. (2014). Long noncoding RNA-EBIC promotes tumor cell invasion by binding to EZH2 and repressing E-cadherin in cervical cancer. PLoS One 9(7): e100340. link pubmed

© Bioinformatics Group of XTBG