Linc-ITGB1

Gene basic information

SymbolLinc-ITGB1
Tissuebreast,gallbladder,
Cancerbreast cancer,gallbladder cancer,


Description

LncRNA linc-ITGB1 is higher in breast cancer (1) and gallbladder cancer (2). It regulates cancer cell proliferation, migration and invasion via regulating Cdc25C, Cyclin B1, E-cadherin, N-cadherin, vimentin and Snail.


Cancer related information

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LncRNA tissue cancer type expression level oncogene/suppress gene pathway binding gene/factor associated gene/factor proliferation apoptosis migration EMT invasion metastasis prognosis tag PMID
0 Linc-ITGB1 gallbladder gallbladder cancer up onco + + + + 25893892
1 Linc-ITGB1 breast breast cancer up onco Cdc25C+,Cyclin B1+,E-cadherin-,N-cadherin+,vimentin+,Snail+ + + + 26601916

Literature

[1]. Yan M, Zhang L, Li G, Xiao S, Dai J, et al. (2017). Long noncoding RNA linc-ITGB1 promotes cell migration and invasion in human breast cancer. Biotechnol Appl Biochem 64(1): 5-13. link pubmed
[2]. Wang L, Zhang Y, Lv W, Lu J, Mu J, et al. (2015). Long non-coding RNA Linc-ITGB1 knockdown inhibits cell migration and invasion in GBC-SD/M and GBC-SD gallbladder cancer cell lines. Chem Biol Drug Des 86(5): 1064-71. link pubmed



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