LINC00657

Gene basic information

symbol NORAD
name non-coding RNA activated by DNA damage
location 20q11.23
alias_symbol
alias_name
Tissuebreast,
Cancerbreast cancer,


Description

LINC00657 is up-regulated in breast cancer. Its upregulation is associated with poor overall survival due to the copy number alteration. LINC00657 knockout significantly suppresses tumor cell growth and proliferation, suggesting that it plays an oncogenic role (1).


Cancer related information

download as excel csv txt

LncRNA tissue cancer type expression level oncogene/suppress gene pathway binding gene/factor associated gene/factor proliferation apoptosis migration EMT invasion metastasis prognosis tag PMID
0 LINC00657 breast breast cancer up onco + - 26942882

Expression profile

adipose adrenal brain breast colon heart kidney leukocyte liver lung lymph node ovary prostate skeletal muscle testis thyroid tissue 0 50 100 150 200 250 300 fpkm 130.0 102.0 319.0 177.0 93.0 121.0 119.0 99.0 45.0 112.0 59.0 180.0 96.0 89.0 103.0 182.0 LINC00657 

Expression profile in human body map

TCGA-BLCA TCGA-BRCA TCGA-CESC TCGA-HNSC TCGA-KICH TCGA-KIRC TCGA-KIRP TCGA-LIHC TCGA-LUAD TCGA-LUSC TCGA-PRAD TCGA-STAD TCGA-THCA TCGA-UCEC tissue 0 20 40 60 80 100 fpkm LINC00657  type normal tumor

Expression profile in TCGA


Sequence

External link



Literature

[1]. Liu H, Li J, Koirala P, Ding X, Chen B, et al. (2016). Long non-coding RNAs as prognostic markers in human breast cancer. Oncotarget 7(15): 20584-96. link pubmed



© Bioinformatics Group of XTBG