LINC01207

Gene basic information

symbol LINC01207
name long intergenic non-protein coding RNA 1207
location 4q32.3
alias_symbol
alias_name
Tissuelung,
Cancerlung adenocarcinoma,


Description

LINC01207 is up-regulated in lung adenocarcinoma (LAD) but no significant difference is observed in lung squamous cell cancer (LSCC). The expression level of LINC01207 is associated with TNM stage and survival time. LINC01207 can promote cell proliferation and inhibit apoptosis. Further study finds that LINC01207 inhibits apoptosis by binding to EZH2 and mediating H3K27-me3 at the promoter region of Bad (1).


Cancer related information

download as excel csv txt

LncRNA tissue cancer type expression level oncogene/suppress gene pathway binding gene/factor associated gene/factor proliferation apoptosis migration EMT invasion metastasis prognosis tag PMID
0 LINC01207 lung lung adenocarcinoma up onco EZH2 Bad- + - - 26693067

Expression profile

adipose adrenal brain breast colon heart kidney leukocyte liver lung lymph node ovary prostate skeletal muscle testis thyroid tissue 0.0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 fpkm 0.1 0.1 0.1 0.1 0.8 0.0 0.1 0.0 0.0 0.5 0.1 0.2 0.8 0.1 0.1 0.1 LINC01207

Expression profile in human body map

TCGA-BLCA TCGA-BRCA TCGA-CESC TCGA-HNSC TCGA-KICH TCGA-KIRC TCGA-KIRP TCGA-LIHC TCGA-LUAD TCGA-LUSC TCGA-PRAD TCGA-STAD TCGA-THCA TCGA-UCEC tissue 0 1 2 3 4 5 6 7 fpkm LINC01207 type normal tumor

Expression profile in TCGA


Genomic feature visualization


Sequence

External link



Literature

[1]. Wang G, Chen H, Liu J (2015). The long noncoding RNA LINC01207 promotes proliferation of lung adenocarcinoma. Am J Cancer Res 5(10): 3162-73. link pubmed



© Bioinformatics Group of XTBG