LINC01852

Gene basic information

symbol LINC01852
name long intergenic non-protein coding RNA 1852
location 15q14
alias_symbol ENST00000434223
alias_name
Tissuelung,
Cancernon-small-cell lung cancer,


Description

LINC01852 is greatly down-regulated in cancer tissues, and correlated with tumor diameter, lymph node metastasis and TNM stage. LINC01852 overexpression suppresses the proliferation, migration and ENT in non-small cell lung cancer (NSCLC) cell lines. Further studies find that P21 protein level is increased with LINC01852 overexpression. Moreover, LINC01852 overexpressing results in a marked increase in the E-cadherin protein level and a significantly decrease in expression of N-cadherin and vimentin (1).


Cancer related information

download as excel csv txt

LncRNA tissue cancer type expression level oncogene/suppress gene pathway binding gene/factor associated gene/factor proliferation apoptosis migration EMT invasion metastasis prognosis tag PMID
0 LINC01852 lung non-small-cell lung cancer down TS p21+,E-cadherin+,N-cadherin-,vimentin- - + - - 26883250

Expression profile

adipose adrenal brain breast colon heart kidney leukocyte liver lung lymph node ovary prostate skeletal muscle testis thyroid tissue 0.00 0.25 0.50 0.75 1.00 1.25 1.50 1.75 2.00 fpkm 0.4 0.9 0.4 1.0 0.2 0.2 0.3 0.2 0.1 0.4 0.4 1.0 0.3 0.0 1.0 2.0 LINC01852

Expression profile in human body map

TCGA-BLCA TCGA-BRCA TCGA-CESC TCGA-HNSC TCGA-KICH TCGA-KIRC TCGA-KIRP TCGA-LIHC TCGA-LUAD TCGA-LUSC TCGA-PRAD TCGA-STAD TCGA-THCA TCGA-UCEC tissue 0.0 0.2 0.4 0.6 0.8 1.0 1.2 fpkm LINC01852 type normal tumor

Expression profile in TCGA


Genomic feature visualization


Sequence

External link



Literature

[1]. Chai X, Ye X, Song Y (2016). Long noncoding RNA ENST00000434223 suppressed tumor progression in non-small cell lung cancer. Tumour Biol 37(8): 10851-60. link pubmed



© Bioinformatics Group of XTBG