Lnc-CC3

Gene basic information

SymbolLnc-CC3
Tissuecervix,
Cancercervical cancer,


Description

LncRNA CC3 is up-regulated in cervical cancer and higher in stage III specimens compared to the other stages. Lnc-CC3 can promote cell migration and invasion. Moreover, it can affect EMT via increasing slug expression and reducing the expression of the epithelial cell marker E-cadherin (1).


Cancer related information

download as excel csv txt

LncRNA tissue cancer type expression level oncogene/suppress gene pathway binding gene/factor associated gene/factor proliferation apoptosis migration EMT invasion metastasis prognosis tag PMID
0 Lnc-CC3 cervix cervical cancer up onco Slug+,E-cadherin- + + + 27223436

Literature

[1]. Jiang B, Sun R, Fang S, Qin C, Pan X, et al. (2016). Lnc-CC3 increases metastasis in cervical cancer by increasing Slug expression. Oncotarget 7(27): 41650-41661. link pubmed



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