Gene basic information

Cancerhepatic cancer,


LncRNA WRAP53 is significantly higher in sera of hepatic carcinoma (HCC) than those with chronic hepatitis C virus (HCV) infection or healthy volunteers. Increased expression of WRAP53 is associated with advanced clinical parameters in HCC. Besides, WRAP53 is a significant independent prognostic marker in relapse-free survival. In addition, UCA1 and WRAP53 up-regulation may serve as novel serum biomarkers for HCC diagnosis and prognosis (1).

Cancer related information

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LncRNA tissue cancer type expression level oncogene/suppress gene pathway binding gene/factor associated gene/factor proliferation apoptosis migration EMT invasion metastasis prognosis tag PMID
0 lnc-WRAP53 liver hepatic cancer up / 26551349


[1]. Kamel MM, Matboli M, Sallam M, Montasser IF, Saad AS, et al. (2016). Investigation of long noncoding RNAs expression profile as potential serum biomarkers in patients with hepatocellular carcinoma. Transl Res 168: 134-45. link pubmed

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