MIR100HG

Gene basic information

symbol MIR100HG
name mir-100-let-7a-2-mir-125b-1 cluster host gene
location 11q24.1
alias_symbol AGD1|lncRNA-N2|linc-NeD125
alias_name adipogenesis down-regulated transcript 1|lncRNA neuronal 2|neuronal differentiation lncRNA hosting miR-125
Tissuebone marrow,nervous system,
Canceracute megakaryocytic leukemia,neuroblastoma,


Description

LncRNA MIR100HG is higher in acute megakaryocytic leukemia (AMKL) (1), lower in neuroblastoma (2). It can regulate cancer cell proliferation.


Cancer related information

download as excel csv txt

LncRNA tissue cancer type expression level oncogene/suppress gene pathway binding gene/factor associated gene/factor proliferation apoptosis migration EMT invasion metastasis prognosis tag PMID
0 MIR100HG bone marrow acute megakaryocytic leukemia up onco + + 25027842
1 MIR100HG nervous system neuroblastoma down TS Bcl-2+ - 26480000

Expression profile

adipose adrenal brain breast colon heart kidney leukocyte liver lung lymph node ovary prostate skeletal muscle testis thyroid tissue 0 5 10 15 20 25 30 35 fpkm 4.0 3.0 8.0 5.0 11.0 4.0 2.0 0.0 0.1 15.0 9.0 36.0 19.0 0.8 9.0 12.0 MIR100HG

Expression profile in human body map

TCGA-BLCA TCGA-BRCA TCGA-CESC TCGA-HNSC TCGA-KICH TCGA-KIRC TCGA-KIRP TCGA-LIHC TCGA-LUAD TCGA-LUSC TCGA-PRAD TCGA-STAD TCGA-THCA TCGA-UCEC tissue 0 2 4 6 8 fpkm MIR100HG type normal tumor

Expression profile in TCGA


Genomic feature visualization


Sequence

External link



Literature

[1]. Emmrich S, Streltsov A, Schmidt F, Thangapandi VR, Reinhardt D, et al. (2014). LincRNAs MONC and MIR100HG act as oncogenes in acute megakaryoblastic leukemia. Mol Cancer 13: 171. link pubmed
[2]. Bevilacqua V, Gioia U, Di Carlo V, Tortorelli AF, Colombo T, et al. (2015). Identification of linc-NeD125, a novel long non coding RNA that hosts miR-125b-1 and negatively controls proliferation of human neuroblastoma cells. RNA Biol 12(12): 1323-37. link pubmed



© Bioinformatics Group of XTBG