|name||prostate cancer associated transcript 6 (non-protein coding)|
|alias_name||prostate cancer-associated noncoding RNA 1|
LncRNA PCAT6 is significantly increased in lung cancer tissues and correlates with metastasis and prognosis of lung cancer patients. PCAT6 significantly promotes cellular proliferation and metastasis, as well as inhibits early apoptosis of lung cancer cells. Molecular analysis reveals that PCAT6 regulates the expression of two pivotal cancer-related proteins, c-Myc and p53, in lung cancer cells. However, PCAT6 is not directly combined with c-Myc and p53 as confirmed by RNA immune-precipitation (1).
|LncRNA||tissue||cancer type||expression level||oncogene/suppress gene||pathway||binding gene/factor||associated gene/factor||proliferation||apoptosis||migration||EMT||invasion||metastasis||prognosis||tag||PMID|
Expression profile in human body map
Expression profile in TCGA