RPL13AP23

Gene basic information

symbol RPL13AP23
name ribosomal protein L13a pseudogene 23
location 12q13.3
alias_symbol
alias_name
Tissuepancreas,
Cancerpancreatic cancer,


Description

RPL13AP23 expression level is remarkably decreased in pancreatic ductal adenocarcinoma (PDAC) tissues and associated with tumor node metastasis stage, lymph node metastasis and prognosis. Besides, enforced expression of RPL13AP23 suppresses PDAC cells' invasion. Moreover, overexpression of RPL13AP23 significantly increases both mRNA and protein level of OS-9. The lncRNA RPL13AP23 inhibits tumor invasion by suppressing HIF-1α expression through modulating OS-9 function (1).


Cancer related information

download as excel csv txt

LncRNA tissue cancer type expression level oncogene/suppress gene pathway binding gene/factor associated gene/factor proliferation apoptosis migration EMT invasion metastasis prognosis tag PMID
0 RPL13AP23 pancreas pancreatic cancer down TS HIF-1α-,OS-9+ - + 25314054

Expression profile

adipose adrenal brain breast colon heart kidney leukocyte liver lung lymph node ovary prostate skeletal muscle testis thyroid tissue 0.000 0.025 0.050 0.075 0.100 0.125 0.150 0.175 0.200 fpkm 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 RPL13AP23

Expression profile in human body map

Genomic feature visualization


Sequence

External link



Literature

[1]. Sun YW, Chen YF, Li J, Huo YM, Liu DJ, et al. (2014). A novel long non-coding RNA ENST00000480739 suppresses tumour cell invasion by regulating OS-9 and HIF-1α in pancreatic ductal adenocarcinoma. Br J Cancer 111(11): 2131-41. link pubmed



© Bioinformatics Group of XTBG