|Cancer||acute myelocytic leukemia,|
LncRNA RUNXOR is transcribed as unspliced transcript from an upstream overlapping promoter. RUNXOR is up-regulated in acute myelocytic leukemia (AML) samples and in response to Ara-C treatment. RUNXOR utilizes its 3'-terminal fragment to directly interact with the RUNX1 promoter and enhancer, and participates in the orchestration of an intra-chromosomal loop. The 3' region of RUNXOR also participates in long-range inter-chromosomal interactions with chromatin regions that are involved in multiple RUNX1 translocations (1).
|LncRNA||tissue||cancer type||expression level||oncogene/suppress gene||pathway||binding gene/factor||associated gene/factor||proliferation||apoptosis||migration||EMT||invasion||metastasis||prognosis||tag||PMID|
|0||RUNXOR||bone marrow||acute myelocytic leukemia||up||/||RUNX1,EZH2||24752773|