SNHG12

Gene basic information

symbol SNHG12
name small nucleolar RNA host gene 12
location 1p35.3
alias_symbol PNAS-123|LINC00100|ASLNC04080
alias_name long intergenic non-protein coding RNA 100
Tissuebone,endometrium,
Cancerendometrial cancer,osteosarcoma,


Description

SNHG12 is up-regulated in endometrial carcinoma (1) and osteosarcoma tissues and cell lines (2). AMOT mRNA expression level is positively correlated with SNHG12 expression level (2). SNHG12 promotes cell proliferation (1, 2), migration (2) and inhibits apoptosis (1).


Cancer related information

download as excel csv txt

LncRNA tissue cancer type expression level oncogene/suppress gene pathway binding gene/factor associated gene/factor proliferation apoptosis migration EMT invasion metastasis prognosis tag PMID
0 SNHG12 endometrium endometrial cancer up onco + - 25695231
1 SNHG12 bone osteosarcoma up onco AMOT+ + + 26486328

Expression profile

adipose adrenal brain breast colon heart kidney leukocyte liver lung lymph node ovary prostate skeletal muscle testis thyroid tissue 0 1 2 3 4 5 6 7 8 fpkm 1.0 8.0 1.0 1.0 0.8 0.7 2.0 0.9 0.7 6.0 8.0 4.0 3.0 1.0 1.0 2.0 SNHG12

Expression profile in human body map

TCGA-BLCA TCGA-BRCA TCGA-CESC TCGA-HNSC TCGA-KICH TCGA-KIRC TCGA-KIRP TCGA-LIHC TCGA-LUAD TCGA-LUSC TCGA-PRAD TCGA-STAD TCGA-THCA TCGA-UCEC tissue 0 1 2 3 4 5 6 fpkm SNHG12 type normal tumor

Expression profile in TCGA


Genomic feature visualization


Sequence

External link



Literature

[1]. Zhai W, Li X, Wu S, Zhang Y, Pang H, et al. (2015). Microarray expression profile of lncRNAs and the upregulated ASLNC04080 lncRNA in human endometrial carcinoma. Int J Oncol 46(5): 2125-37. link pubmed
[2]. Ruan W, Wang P, Feng S, Xue Y, Li Y (2016). Long non-coding RNA small nucleolar RNA host gene 12 (SNHG12) promotes cell proliferation and migration by upregulating angiomotin gene expression in human osteosarcoma cells. Tumour Biol 37(3): 4065-73. link pubmed



© Bioinformatics Group of XTBG