SNHG15

Gene basic information

symbol SNHG15
name small nucleolar RNA host gene 15
location 7p13
alias_symbol FLJ38860|MYO1GUT|Linc-Myo1g
alias_name MYO1G upstream transcript
Tissueliver,stomach,
Cancergastric cancer,hepatic cancer,


Description

LncRNA SNHG15 is up-regulated in gastric cancer (GC) (1) and hepatocellular carcinoma (HCC) (2). Furthermore, increased SNHG15 expression is correlated with clinicopathologic feature and prognosis (2, 1). Functionally, SNHG15 expression can promote cell proliferation and invasion and inhibit apoptosis. Mechanistically, SNHG15 promotes cell proliferation and invasion in GC cells partly via regulating MMP2 and MMP9 protein expression (1).


Cancer related information

download as excel csv txt

LncRNA tissue cancer type expression level oncogene/suppress gene pathway binding gene/factor associated gene/factor proliferation apoptosis migration EMT invasion metastasis prognosis tag PMID
0 SNHG15 stomach gastric cancer up onco MMP2+,MMP9+ + - + - 26662309
1 SNHG15 liver hepatic cancer up / - 27212162

Expression profile

adipose adrenal brain breast colon heart kidney leukocyte liver lung lymph node ovary prostate skeletal muscle testis thyroid tissue 0 2 4 6 8 fpkm 1.0 9.0 2.0 2.0 1.0 0.6 2.0 2.0 1.0 5.0 6.0 4.0 3.0 0.4 2.0 2.0 SNHG15

Expression profile in human body map

TCGA-BLCA TCGA-BRCA TCGA-CESC TCGA-HNSC TCGA-KICH TCGA-KIRC TCGA-KIRP TCGA-LIHC TCGA-LUAD TCGA-LUSC TCGA-PRAD TCGA-STAD TCGA-THCA TCGA-UCEC tissue 0 1 2 3 4 5 6 fpkm SNHG15 type normal tumor

Expression profile in TCGA


Genomic feature visualization


Sequence

External link



Literature

[1]. Chen SX, Yin JF, Lin BC, Su HF, Zheng Z, et al. (2016). Upregulated expression of long noncoding RNA SNHG15 promotes cell proliferation and invasion through regulates MMP2/MMP9 in patients with GC. Tumour Biol 37(5): 6801-12. link pubmed
[2]. Zhang JH, Wei HW, Yang HG (2016). Long noncoding RNA SNHG15, a potential prognostic biomarker for hepatocellular carcinoma. Eur Rev Med Pharmacol Sci 20(9): 1720-4. link pubmed



© Bioinformatics Group of XTBG