SNHG3

Gene basic information

symbol SNHG3
name small nucleolar RNA host gene 3
location 1p35.3
alias_symbol U17HG|U17HG-A|NCRNA00014
alias_name non-protein coding RNA 14
Tissueliver,
Cancerhepatic cancer,


Description

LncRNA SNHG3 is significantly up-regulated in hepatocellular carcinoma (HCC) tissues, which is consistent with the results of two independent HCC cohorts from The Cancer Genome Atlas (TCGA) and Oncomine databases. Furthermore, SNHG3 expression is significantly correlated with tumor size, portal vein tumor thrombus and relapse. The high expression level of SNHG3 is markedly correlated with overall survival, recurrence-free survival and disease-free survival. Besides, multivariate analysis indicates that SNHG3 expression is an independent prognostic factor for HCC patients (1).


Cancer related information

download as excel csv txt

LncRNA tissue cancer type expression level oncogene/suppress gene pathway binding gene/factor associated gene/factor proliferation apoptosis migration EMT invasion metastasis prognosis tag PMID
0 SNHG3 liver hepatic cancer up / - 26373735

Expression profile

adipose adrenal brain breast colon heart kidney leukocyte liver lung lymph node ovary prostate skeletal muscle testis thyroid tissue 0 2 4 6 8 10 12 14 fpkm 2.0 13.0 2.0 2.0 2.0 1.0 4.0 2.0 2.0 9.0 12.0 9.0 4.0 0.7 1.0 14.0 SNHG3

Expression profile in human body map

TCGA-BLCA TCGA-BRCA TCGA-CESC TCGA-HNSC TCGA-KICH TCGA-KIRC TCGA-KIRP TCGA-LIHC TCGA-LUAD TCGA-LUSC TCGA-PRAD TCGA-STAD TCGA-THCA TCGA-UCEC tissue 0 1 2 3 4 5 fpkm SNHG3 type normal tumor

Expression profile in TCGA


Sequence

External link



Literature

[1]. Zhang T, Cao C, Wu D, Liu L (2016). SNHG3 correlates with malignant status and poor prognosis in hepatocellular carcinoma. Tumour Biol 37(2): 2379-85. link pubmed



© Bioinformatics Group of XTBG