| symbol | SNHG3 |
| name | small nucleolar RNA host gene 3 |
| location | 1p35.3 |
| alias_symbol | U17HG|U17HG-A|NCRNA00014 |
| alias_name | non-protein coding RNA 14 |
| Tissue | liver, |
| Cancer | hepatic cancer, |
LncRNA SNHG3 is significantly up-regulated in hepatocellular carcinoma (HCC) tissues, which is consistent with the results of two independent HCC cohorts from The Cancer Genome Atlas (TCGA) and Oncomine databases. Furthermore, SNHG3 expression is significantly correlated with tumor size, portal vein tumor thrombus and relapse. The high expression level of SNHG3 is markedly correlated with overall survival, recurrence-free survival and disease-free survival. Besides, multivariate analysis indicates that SNHG3 expression is an independent prognostic factor for HCC patients (1).
| LncRNA | tissue | cancer type | expression level | oncogene/suppress gene | pathway | binding gene/factor | associated gene/factor | proliferation | apoptosis | migration | EMT | invasion | metastasis | prognosis | tag | PMID | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0 | SNHG3 | liver | hepatic cancer | up | / | - | 26373735 |
Expression profile in human body map
Expression profile in TCGA
| entrez_id | 8420 |
| ucsc_id | uc031tvj.2 |
| Ensembl_gene_id | ENSG00000242125 |
| HGNC_id | HGNC:10118 |
| Omim_id | 603238 |
| cosmic | |
| lncrnadb | snhg3 |