Gene basic information

Tissuenervous system,


LncRNA TSLC1-AS1 and TSLC1 are both down-regulated in glioma tissue samples. Functionally, TSLC1-AS1 inhibits cell proliferation, migration and invasion. Moreover, TSLC1-AS1 is positively correlated with TSLC1. Besides, TSLC1-AS1 is also positively correlated with other tumor suppressors NF1, VHL, PIK3R1 and negatively correlated with the oncogene BRAF (1).

Cancer related information

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LncRNA tissue cancer type expression level oncogene/suppress gene pathway binding gene/factor associated gene/factor proliferation apoptosis migration EMT invasion metastasis prognosis tag PMID
0 TSLC1-AS1 nervous system glioma down TS NF1+,VHL+,PIK3R1+,BRAF-,TSLC1+ - - - 25031725


[1]. Qin X, Yao J, Geng P, Fu X, Xue J, et al. (2014). LncRNA TSLC1-AS1 is a novel tumor suppressor in glioma. Int J Clin Exp Pathol 7(6): 3065-72. link pubmed

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