LncRNA TUC339 is up-regulated in hepatic carcinoma (HCC). TUC339 is functionally implicated in modulating tumor cell growth and adhesion. Suppression of TUC339 by siRNA reduces HCC cell proliferation, clonogenic growth, and growth in soft agar. Thus, inter-cellular transfer of TUC339 represents a unique signaling mechanism by which tumor cells can promote HCC growth and spread (1).
|LncRNA||tissue||cancer type||expression level||oncogene/suppress gene||pathway||binding gene/factor||associated gene/factor||proliferation||apoptosis||migration||EMT||invasion||metastasis||prognosis||tag||PMID|