TUC339

Gene basic information

SymbolTUC339
Tissueliver,
Cancerhepatic cancer,


Description

LncRNA TUC339 is up-regulated in hepatic carcinoma (HCC). TUC339 is functionally implicated in modulating tumor cell growth and adhesion. Suppression of TUC339 by siRNA reduces HCC cell proliferation, clonogenic growth, and growth in soft agar. Thus, inter-cellular transfer of TUC339 represents a unique signaling mechanism by which tumor cells can promote HCC growth and spread (1).


Cancer related information

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LncRNA tissue cancer type expression level oncogene/suppress gene pathway binding gene/factor associated gene/factor proliferation apoptosis migration EMT invasion metastasis prognosis tag PMID
0 TUC339 liver hepatic cancer up onco + 24167654

Literature

[1]. Kogure T, Yan IK, Lin WL, Patel T (2013). Extracellular Vesicle-Mediated Transfer of a Novel Long Noncoding RNA TUC339: A Mechanism of Intercellular Signaling in Human Hepatocellular Cancer. Genes Cancer 4(7-8): 261-72. link pubmed



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