uc002mbe.2

Gene basic information

symbol MIR7-3HG
name MIR7-3 host gene
location 19p13.3
alias_symbol PGSF1|PGSF1a|PGSF1b|Huh7|uc002mbe.2
alias_name pituitary gland specific factor 1a|pituitary gland specific factor 1b
Tissueliver,
Cancerhepatic cancer,


Description

LncRNA uc002mbe.2 expression level is significantly lower in the hepatic carcinoma (HCC) cell lines and liver cancer tissues. The histone deacetylase inhibitor (TSA) induces uc002mbe.2 expression that is positively correlated with the apoptotic effect of TSA in HCC cells. In addition, knocking down the expression of uc002mbe.2 significantly reduces TSA-induced apoptosis of Huh7cells (1).


Cancer related information

download as excel csv txt

LncRNA tissue cancer type expression level oncogene/suppress gene pathway binding gene/factor associated gene/factor proliferation apoptosis migration EMT invasion metastasis prognosis tag PMID
0 uc002mbe.2 liver hepatic cancer down TS + 23643933

Expression profile

adipose adrenal brain breast colon heart kidney leukocyte liver lung lymph node ovary prostate skeletal muscle testis thyroid tissue 0.0 0.5 1.0 1.5 2.0 2.5 3.0 3.5 4.0 fpkm 0.1 0.1 3.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.1 4.0 0.1 uc002mbe.2

Expression profile in human body map

TCGA-BLCA TCGA-BRCA TCGA-CESC TCGA-HNSC TCGA-KICH TCGA-KIRC TCGA-KIRP TCGA-LIHC TCGA-LUAD TCGA-LUSC TCGA-PRAD TCGA-STAD TCGA-THCA TCGA-UCEC tissue 0.00 0.05 0.10 0.15 0.20 fpkm uc002mbe.2 type normal tumor

Expression profile in TCGA


Genomic feature visualization


Sequence

External link



Literature

[1]. Yang H, Zhong Y, Xie H, Lai X, Xu M, et al. (2013). Induction of the liver cancer-down-regulated long noncoding RNA uc002mbe.2 mediates trichostatin-induced apoptosis of liver cancer cells. Biochem Pharmacol 85(12): 1761-9. link pubmed



© Bioinformatics Group of XTBG