| Symbol | uc.63 |
| Tissue | breast, |
| Cancer | breast cancer, |
Transcribed ultra-conserved regions (T-UCRs) are long non-coding RNAs (lncRNA) encoded by a subset of long ultra-conserved stretches in the human genome. uc.63 is one specific T-UCRs which is up-regulated and associated with bad outcome in luminal A subtype of breast cancer patients. uc.63 is localized in the third intron of exportin-1 gene (XPO1) and is transcribed in the same orientation of its host gene. Moreover, uc.63 can inhibit apoptosis of breast cancer cells (1).
| LncRNA | tissue | cancer type | expression level | oncogene/suppress gene | pathway | binding gene/factor | associated gene/factor | proliferation | apoptosis | migration | EMT | invasion | metastasis | prognosis | tag | PMID | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0 | uc.63 | breast | breast cancer | up | onco | - | 27447964 |