UNMIBC

Gene basic information

SymbolUNMIBC
Tissuebladder,
Cancerbladder cancer,


Description

LncRNA UNMIBC is up-regulated in the primary non-muscle invasive bladder cancer and significantly associated with recurrence. Moreover, UNMIBC has a key role in G0/G1 arrest. Furthermore, RNA and chromatin immune-precipitation assays demonstrate that UNMIBC is physically associated with EZH2 and SUZ12, leading to an altered histone H3 lysine 27 methylation status of target genes (1).


Cancer related information

download as excel csv txt

LncRNA tissue cancer type expression level oncogene/suppress gene pathway binding gene/factor associated gene/factor proliferation apoptosis migration EMT invasion metastasis prognosis tag PMID
0 UNMIBC bladder bladder cancer up onco EZH2,SUZ12 + + 27267320

Literature

[1]. Zhang S, Zhong G, He W, Yu H, Huang J, et al. (2016). lncRNA Up-Regulated in Nonmuscle Invasive Bladder Cancer Facilitates Tumor Growth and Acts as a Negative Prognostic Factor of Recurrence. J Urol 196(4): 1270-8. link pubmed



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